Lancefield's Group C streptococci rarely cause disease in humans but are known to colonize the skin, the newborn umbilicus and the mucosal surfaces of the nose, throat, vagina and rectum.1–5 As many as 3% of healthy humans can be colonized by Group C streptococci although few data regarding carriage rates are available.6 Hemming and Darling7 recovered Group C streptococci from 109 (1.5%) of 7328 throat cultures obtained from children and adults. Drusin et al,5 reported isolating a single Group C species from the umbilical cultures of 14 of 22 newborns, all of whom remained well. The purpose of this report is to illustrate the manifestations of infection with Group C streptococci in three previously healthy children and to review the pediatric literature on this topic.