Evidence of increased chloroquine sensitivity in Thai isolates of Plasmodium falciparum
- 1 January 1988
- journal article
- Published by Oxford University Press (OUP) in Transactions of the Royal Society of Tropical Medicine and Hygiene
- Vol. 82 (1) , 37-38
- https://doi.org/10.1016/0035-9203(88)90255-6
Abstract
Sensitivity of Thai isolates of Plasmodium falciparum to chloroquine collected over the years 1978-1986 was measured by two methods: (i) by growth of previously cultured isolates for 72 h in presence of drug, and (ii) by the WHO standard in vitro microtest. During this period there were signs of a gradual increase in drug sensitivity, coinciding with the withdrawal of chloroquine for treatment of falciparum malaria in Thailand.Keywords
This publication has 3 references indexed in Scilit:
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- Plasmodium chabaudi: Genetics of resistance to chloroquineExperimental Parasitology, 1981
- Human Malaria Parasites in Continuous CultureScience, 1976