ON THE PATHOGENESIS AND HEMODYNAMICAL SIGNIFICANCE OF THE VENOARTERIAL REACTION IN DIABETIC MICRO-CIRCULATION DISTURBANCE

  • 1 January 1982
    • journal article
    • research article
    • Vol. 41  (5) , 457-464
Abstract
In human diabetes mellitus, functional microangiopathy starts with venule dilatation, the cause of which is unknown. The results of comparative measurements of animals with alloxan diabetes verify an increase in the arteriovenous caliber relation. These alterations are due to venule congestion and passive dilatation as a consequence of red cell aggregation and an increase in the viscosity of blood. The increase of the flow resistance on the postcapillary side depends only on rheological but not on nervous-humoral factors, which lead to increased constrictions of the arterioles.

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