The Effect of Sodium Selenite on the Blood Sugar and Liver Glycogen of Rats and Rabbits
- 1 January 1941
- journal article
- research article
- Published by JSTOR in Public Health Reports®
- Vol. 56 (8) , 345-352
- https://doi.org/10.2307/4583627
Abstract
Intraven. doses of Na selenite greater than 5.0 mg. per kg. cause an increase in the blood sugar conc. of the rat, and 10.0 mg. per kg. cause a decrease in liver glycogen conc. Subcut. doses of Na selenite greater than 3.0 mg. per kg. cause a marked rise in the blood sugar of well-fed rabbits reaching values of 400 to 600 mg. %. The same doses sometimes cause a slight rise in the blood sugar of fasted rabbits, followed occasionally by an abrupt fall just preceding the death of the animal. Fasted rats have a lower glucose tolerance after receiving an inj. of Na selenite and the rate of deposition of liver glycogen from injected glucose is slower for 2 or more hrs.This publication has 1 reference indexed in Scilit:
- The Influence of Diet on the Chronic Toxicity of SeleniumPublic Health Reports®, 1939