Incorporation and Conversion of Lysine-2-C14 in Rat Biopsy-Connective Tissue

Abstract
Lysine-2-C14 was incorporated and hydroxylated in connective tissue incubated in Krebs-Henseleit medium for 12 hours. The specific activity of collagenous and non-collagenous protein in the tissue studied in vitro was greater than that in tissue studied in vivo. Hydroxylation of labeled lysine appeared to occur more effectively in connective tissue of rats given labeled lysine intraperitoneally than in connective tissue incubated with lysine-2-C14.

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