Enzymatic Formation of Cardiolipin from Phosphatidylglycerol by the Transphosphatidylation Mechanism Catalyzed by Phospholipase D
- 1 June 1973
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Biochemistry
- Vol. 51 (6) , 747-753
- https://doi.org/10.1139/o73-093
Abstract
The enzymatic formation of cardiolipin-3H from purified phosphatidylglycerol-2′-3H catalyzed by phospholipase D is described. Some general conditions for this formation are studied and discussed. The formation of cardiolipin is independent of cytidine coenzymes and takes place by a transphosphatidylation reaction mechanism in which phosphatidylglycerol serves as the acceptor and as the donor of the phosphatidyl group.Keywords
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