Localized1Hin vivo NMR spectroscopy of small-volume elements in human brain at 1.5 T

Abstract
Localized in vivo proton NMR spectra of volume elements of minimal size (13 × 13 × 13 mm3) were obtained in human brain with a whole‐body imager working at 1.5‐T field strength. By use of an optimized version of the 90°‐180°‐180° volume selection method, well‐resolved proton spectra were acquired within 9 min and a comparison of spectra with different echo times (135 and 270 ms) was possible within 20 min. © 1990 Academic Press, Inc.