Time???Series Designs in Clinical Nursing Research

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Abstract
Prospective time-series research methods require substantially greater commitment and effort from both subjects and investigators compared to designs that involve one-time data collection. Human issues such as retention, confidentiality, burnout, and clinician-researcher role conflict have not been adequately addressed in existing literature on time-series methodology. To maintain the scientific integrity of a time-series design and minimize unnecessary costs associated with subject and staff attrition, these issues should not be overlooked.
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