Some Observations on the Larval Growth Rate and Viability of Two Tumor Strains of Drosophila melanogaster
- 19 March 1948
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 107 (2777) , 296-297
- https://doi.org/10.1126/science.107.2777.296
Abstract
Two tumor strains, bw tu and st sr es ro ca, tu-36a, as well as a control strain, were studied. Cultures were incubated at 20, 25, and 30 C. From them, eggs were collected and transferred to dishes with molasses agar inoculated with yeast. They were reincubated, allowed to hatch, and the larvae allowed to develop. Time of pupation was used to compare growth rate. The end point was the time when the number of pupae equaled half the number of eggs started. Neither tumor strain had even 50% viability at 30 C. The reduction in tumor incidence was accompanied by reduced viability. The development in all strains was slowest at 20 C. Both tumor strains developed more slowly at the higher temp. than did the wild control, but more rapidly at lower temp. The bw tu strain was the least retarded at 20 C. Viability was no different in the 3 strains at the lower temp. levels.Keywords
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