GlyProt: in silico glycosylation of proteins
Open Access
- 1 July 2005
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 33 (Web Server) , W214-W219
- https://doi.org/10.1093/nar/gki385
Abstract
GlyProt ( http://www.glycosciences.de/glyprot/ ) is a web-based tool that enables meaningful N -glycan conformations to be attached to all the spatially accessible potential N-glycosylation sites of a known three-dimensional (3D) protein structure. The probabilities of physicochemical properties such as mass, accessible surface and radius of gyration are calculated. The purpose of this service is to provide rapid access to reliable 3D models of glycoproteins, which can subsequently be refined by using more elaborate simulations and validated by comparing the generated models with experimental data.Keywords
This publication has 13 references indexed in Scilit:
- Carbohydrate Structure Suite (CSS): analysis of carbohydrate 3D structures derived from the PDBNucleic Acids Research, 2004
- Finishing the euchromatic sequence of the human genomeNature, 2004
- Data mining the protein data bank: automatic detection and assignment of carbohydrate structuresCarbohydrate Research, 2003
- Statistical analysis of the protein environment of N-glycosylation sites: implications for occupancy, structure, and foldingGlycobiology, 2003
- Biases and complex patterns in the residues flanking protein N-glycosylation sitesGlycobiology, 2003
- Rapid generation of a representative ensemble of N-glycan conformations.2002
- Structure, Conformation, and Dynamics of Bioactive Oligosaccharides: Theoretical Approaches and Experimental ValidationsChemical Reviews, 2000
- On the frequency of protein glycosylation, as deduced from analysis of the SWISS-PROT databaseBiochimica et Biophysica Acta (BBA) - General Subjects, 1999
- Computational carbohydrate chemistry: what theoretical methods can tell usGlycoconjugate Journal, 1998
- Stereochemistry of the N-glycosylation sites in glycoproteinsProtein Engineering, Design and Selection, 1995