THE LARGEST ORGAN

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To the Editor:— In the article entitled "Modern Physiologic Concepts: Their Application to the Treatment of Diseases of the Liver," inThe JournalJune 14, Dr. James F. Weir states "The liver, which is the largest organ in the body..." This is erroneous. An organ is defined as any part of the body having a special function. With this definition, at least one organ, the brain, is just about equal to the liver in weight and at least one other, the skin, is much larger. If we include still other systemized tissues such as bone, muscle and blood, the order of size of organs in weight becomes (1) skeleton, (2) musculature, (3) blood, (4) skin, (5 and 6) liver, brain. Perhaps the skeleton, musculature and blood are not commonly thought of as organs, although there are no good reasons why they should not be so considered, but certainly the skin,

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