Pimozide combined with behavior therapy in the short‐term treatment of anorexia nervosa

Publisher Website
Google Scholar
Abstract
Eighteen female inpatients were included in a double‐blind placebo‐controlled cross‐over study aimed at testing the hypothesis that dopamine blockade may enhance the effectiveness of behavior therapy in the short‐term weight restoration of anorexia nervosa patients. The patients were given a uniform contingency management program and, after a baseline period, they alternatingly (3‐ week periods) received pirnozide (4 or 6 mg) or a placebo. During the first two periods pimozide almost significantly enhanced the weight gain induced by the behavior therapy program and beneficially influenced the patients attitude towards treatment.

This publication has 16 references indexed in Scilit: