Spectroscopic Studies of Metal Ion Mediated Interactions with Components of Nucleic Acids. I. Esr Study of Ternary Copper(II) Complexes of?-Amino Acids and Dipeptides with Adenosine

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Abstract
The formation of the title ternary complexes in aqueous solution has been investigated by electronic and ESR spectroscopy. ESR parameters have been used to compute molecular orbital coefficients. Coordination modes and their influence on metal-ligand bonding have been studied. A characteristic difference between GlyPro and other dipeptides is attributed to the lack of the peptide proton in GlyPro. It is suggested that, at near physiological pH conditions, the nucleoside binds at an equatorial site by displacing a water molecule from the Cu(II) ion.