Thirteen years experience with infusion cholangiography including 1,600 patients indicates it to be the obvious method of choice in performing intravenous cholangiography. The method is safe, almost completely free of untoward reactions, easy to perform, time saving, and makes this valuable examination extremely convenient in a busy radiology department. Its advantages over the conventional method of direct injection are obvious. Utilizing larger doses of contrast medium, slower infusion times and larger volumes of infusing solution provide only a minimal improvement in bile duct opacity and this must be weighed against the prolonged time required to complete the examination.