Mapping the xanthine C8-region of the adenosine A1 receptor with computer graphics
- 25 April 1991
- journal article
- Published by Elsevier in European Journal of Pharmacology: Molecular Pharmacology
- Vol. 206 (4) , 315-323
- https://doi.org/10.1016/0922-4106(91)90116-y
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptorsJournal of Medicinal Chemistry, 1989
- Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positionsJournal of Medicinal Chemistry, 1989
- 8-substituted xanthines as antagonists at A1- and A2-adenosine receptorsBiochemical Pharmacology, 1988
- Hydrogen bonding and rotation barriers: A comparison between MNDO and AM1 resultsJournal of Molecular Structure: THEOCHEM, 1988
- Modelling of shape/size selective separations: AM1 rotational barriers for some substituted benzenesJournal of Molecular Structure: THEOCHEM, 1988
- Analogs of 1,3-dipropyl-8-phenylxanthine: enhancement of selectivity at A1-adenosine receptors by aryl substituentsJournal of Medicinal Chemistry, 1986
- Analogs of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptorsJournal of Medicinal Chemistry, 1986
- Synthesis of xanthines as adenosine antagonists, a practical quantitative structure-activity relationship applicationJournal of Medicinal Chemistry, 1985
- Development and use of quantum mechanical molecular models. 76. AM1: a new general purpose quantum mechanical molecular modelJournal of the American Chemical Society, 1985
- 1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptorsJournal of Medicinal Chemistry, 1985