An enantiodivergent synthesis of fused bicyclo[2.2.1]heptane lactones via an asymmetric Diels–Alder reaction
- 1 January 1990
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 4,p. 1233-1234
- https://doi.org/10.1039/p19900001233
Abstract
An enantiodivergent synthesis of the bicyclo[2.2.1]heptane lactone (2) is described, by regioselective reduction of the Diels–Alder adducts (3) and (4) with di-isobutylaluminium hydride followed by reductive elimination of the chiral auxiliary, 10-mercaptoisoborneol (9) through reaction with samarium(II) iodide.This publication has 13 references indexed in Scilit:
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