Molecular Biology of the Cell Cycle
- 1 January 1986
- journal article
- review article
- Published by Taylor & Francis in International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
- Vol. 49 (2) , 219-226
- https://doi.org/10.1080/09553008514552511
Abstract
Genes and cDNA clones have been identified in animal cells that are cell cycle-regulated, i.e. they are preferentially expressed in a phase of the cell cycle. Some of these genes, including four oncogenes, are induced when G0 cells are stimulated to proliferate. Four approaches are described to identify the genes that regulate the transition of cells from a resting to a growing stage. The interrelationship among cell cycle-regulated genes, oncogenes, growth factors and receptors for growth factors points the way to a genetic dissection of cell cycle progression.Keywords
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