Phagocytosis: The Department of Defense

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Abstract
IN the combat against pyogenic infection, the polymorphonuclear leukocytes constitute the first line of defense. They rapidly enter inflammatory foci, whereas the monocytes arrive at a slower pace and then differentiate into macrophages.1 Thus, the monocytes and the mononuclear phagocytes that line the viscera, are a second line of defense. Phagocytosis is the essence of both lines of this defensive system, and the overall manner in which it functions can be divided into seven stages. In the first, the bone marrow produces and mobilizes phagocytes in prodigious numbers. Secondly, bacterial products or inflammatory mediators interact with serum factors, including complement, . . .

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