Metabolism of Women During the Reproductive Cycle

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Abstract
The thiamine intake for 5-day periods, secretion in 24-hour collections of milk, and daily excretion in urine were determined for normal multiparas during the first 10 days postpartum and at various intervals in mature milk production. The intakes of the mothers were comparable, qualitatively, but quantity was determined by appetite. With an average intake of 1.1 mg thiamine per day, the average daily secretion in milk increased from 1 μg on the first day to 95 μg on the tenth day and the excretion in the urine ranged from 200 μg on the first day to 145 μg on the ninth day. During the period of highest secretion of thiamine in milk, 2–3 months postpartum, thiamine in the milk averaged only 8% of the intake. The average volumes of the mature milk secreted during 5-day periods between 2 and 10 months postpartum, ranged from 268 to 1020 ml. The average daily thiamine content of the milk ranged from 30 to 162 mg. Of the thiamine intake accounted for during eighteen 5-day periods for ten women, averages of 23 and 8% appeared in the urine and milk, respectively.

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