The urinary excretion of collagen degradation products by quadriplegic patients and during weightlessness
- 1 March 1977
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Bone and Joint Surgery
- Vol. 59 (2) , 209-212
- https://doi.org/10.2106/00004623-197759020-00013
Abstract
Urinary total hydroxyproline, peptide-bound hydroxyproline, hydroxylysine glycosides and Ca were measured in 3 healthy individuals subjected to weightlessness for 84 days and in 3 young quadriplegic patients. The former group had significant calciuria but no evidence of collagen degradation. The latter group had conspicuous calciuria and excreted large amounts of collagen breakdown products. This documented degradation of matrix may be related to the continuous calciuria, osteoporosis and cutaneous dystrophic changes occurring in quadriplegics.This publication has 2 references indexed in Scilit:
- The Isolation of Identical Hydroxylysyl Glycosides from Hydrolysates of Soluble Collagen and from Human UrineJournal of Biological Chemistry, 1967
- Modifications of a specific assay for hydroxyproline in urineAnalytical Biochemistry, 1967