Triazole Antifungals. V. Synthesis and Antifungal Activities of Some Amides Related to 3-Acylamino-2-aryl-1-triazolyl-2-butanol
- 25 March 1992
- journal article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 40 (3) , 661-665
- https://doi.org/10.1248/cpb.40.661
Abstract
Amides, 2 and 3 related to the potent antifungal triazole-amide 3-acylamino-2-aryl-1-triazolyl-butanol(1) were synthesized starting from the triazole-alcohol 6. The antifungal activity of 2 and 3 against a mouse systemic Candida albicans infection was found to be less potent than that of 1.Keywords
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