Abstract
Six patients with immunoproliferative small intestinal disease (IPSID) were examined endoscopically. The disease involved the duodenum and jejunum and was characterized by the loss of the mucosal circular folds, a thickened cobblestone appearance of the mucosa and multiple sessile polyps. Ulceration of the mucosa was seen in 1 patient. A large ulcerated mass was seen in the 3rd part of the duodenum in 1 patient.