Life is a journey: a genetic look at neocortical development
Top Cited Papers
- 1 May 2002
- journal article
- review article
- Published by Springer Nature in Nature Reviews Genetics
- Vol. 3 (5) , 342-355
- https://doi.org/10.1038/nrg799
Abstract
Although the basic principles of neocortical development have been known for quite some time, it is only recently that our understanding of the molecular mechanisms that are involved has improved. Such understanding has been facilitated by genetic approaches that have identified key proteins involved in neocortical development, which have been placed into signalling pathways by molecular and cell-biological studies. The challenge of current research is to understand the manner in which these various signalling pathways are interconnected to gain a more comprehensive picture of the molecular intricacies that govern neocortical development.Keywords
This publication has 124 references indexed in Scilit:
- Identification of the 23 kDa subunit of tau protein kinase II as a putative activator of cdk5 in bovine brainPublished by Wiley ,2001
- The LIS1-related Protein NUDF of Aspergillus nidulans and Its Interaction Partner NUDE Bind Directly to Specific Subunits of Dynein and Dynactin and to α- and γ-TubulinPublished by Elsevier ,2001
- Mutation analysis of the DCX gene and genotype/phenotype correlation in subcortical band heterotopiaEuropean Journal of Human Genetics, 2001
- Interaction of Cytosolic Adaptor Proteins with Neuronal Apolipoprotein E Receptors and the Amyloid Precursor ProteinJournal of Biological Chemistry, 1998
- Point Mutations and an Intragenic Deletion in LIS1, the Lissencephaly Causative Gene in Isolated Lissencephaly Sequence and Miller-Dieker SyndromeHuman Molecular Genetics, 1997
- A Revision of the Lissencephaly and Miller-Dieker Syndrome Critical Regions in Chromosome 17p13.3Human Molecular Genetics, 1997
- A protein related to extracellular matrix proteins deleted in the mouse mutant reelerNature, 1995
- The ancient regulatory-protein family of WD-repeat proteinsNature, 1994
- A cdc2‐related kinase PSSALRE/cdk5 is homologous with the 30 kDa subunit of tau protein kinase II, a proline‐directed protein kinase associated with microtubuleFEBS Letters, 1993
- Neocortical histogenesis in normal and reeler mice: A developmental study based upon [3H]thymidine autoradiographyDevelopmental Brain Research, 1982