Lung Development and Lecithin Metabolism
- 1 March 1971
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 127 (3) , 413-414
- https://doi.org/10.1001/archinte.1971.00310150073009
Abstract
Normal pulmonary function is dependent upon maturation and maintenance of the biochemical synthesis of a unique specie of disaturated lecithin. The latter effectively combats surface tension and permits the alveolus to remain open at low transpulmonary pressures. The synthesis of this surfactant (antiatelectasis factor) appears reduced by intrauterine asphyxia. This may be etiologically important in respiratory distress syndrome of the newborn.Keywords
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- Surface Properties in Relation to Atelectasis and Hyaline Membrane DiseaseArchives of Pediatrics & Adolescent Medicine, 1959