Immunological Effects of Orchidectomy
- 1 February 1975
- journal article
- Published by Wiley in British Journal of Urology
- Vol. 47 (1) , 89-95
- https://doi.org/10.1111/j.1464-410x.1975.tb03923.x
Abstract
Summary: Orchidectomy caused a non‐specific increase of immunological reactivity in mice evidenced by accelerated rejection of skin allografts, increased response to oxazolone and sheep erythrocytes. These changes were associated with an increase of thymic size.The response to pneumococcal polysaccharide, which depends upon B‐cells, was not increased.Orchidectomised mice showed protection against induced methylcholanthrene sarcomas and transplantable tumours; tumours which are not obviously hormone dependent.Keywords
This publication has 23 references indexed in Scilit:
- THE HORMONAL MECHANISM OF IMMUNOPOTENTIATION IN MICE AFTER ORCHIDECTOMYJournal of Endocrinology, 1974
- Orchidectomy and the immune response II. Response of orchidectomized mice to antigensProceedings of the Royal Society of London. B. Biological Sciences, 1974
- Antitumour effects of Corynebacterium parvum in micePublished by Elsevier ,1974
- T cells: The limiting cells in the initiation of immune responses in normal mouse spleensCellular Immunology, 1972
- Mouse Specific Bone Marrow-derived Lymphocyte Antigen as a Marker for Thymus-independent LymphocytesNature, 1971
- Theta Isoantigen as a Marker of Thymus-derived Lymphocytes in MiceNature, 1969
- Effect of Antilymphocyte Serum on the Growth of Hep 2 and HeLa Cells in MiceNature, 1968
- Clinical Immunologic Study of Malignant DiseaseAnnals of Surgery, 1966
- A Method of Increased Sensitivity for detecting Single Antibody-forming CellsNature, 1965
- ANTIGENIC PROPERTIES OF CHEMICALLY INDUCED TUMORS*Annals of the New York Academy of Sciences, 1962