Asymmetric Synthesis X: The High Enantioselective Synthesis of (R)-α-Substituted Benzylic Amines Via the Modified (+)-Camphor Derivative as Chiral Synthon
- 1 January 1990
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 20 (1) , 15-22
- https://doi.org/10.1080/00397919008054610
Abstract
A new chiral synthon-10-substituted (+)-camphor derivative (III) is synthesized. The alkylation of the (III) with a variety of alkylating agents gives the high enantioselectivity ranging from 72–100%e. e. And the crystal structures of the (III) and (IV) are involved in explaining the results.Keywords
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