MULTIPLE PRIMITIVE ENDOLUMINAL TUMORS OF THE MAIN PANCREATIC DUCT - A CASE WITH EVIDENCE FOR A LINK BETWEEN BENIGN AND MALIGNANT LESIONS

  • 1 February 1988
    • journal article
    • research article
    • Vol. 12  (2) , 163-168
Abstract
A case of multiple villous and, more rarely, tubulovillous adenomas of the main pancreatic duct, associated with a diffuse infiltrating adenocarcinoma of the pancreas in which evidence for a link between these lesions is supported by histopathologic features, is reported in a 53 year old patient. Clinical presentation included abdominal pain, weight loss and chronic diarrhea with steatorrhea related to a pancreatic insufficiency. Retrograde endoscopic pancreatography showed a complete stenosis of the main pancreatic duct located 3 mm beyond the ampulla of Vater. CT scan showed a heterogeneous cephalic pancreatic tumor with extensive enlargement of the main pancreatic duct. After total pancreatectomy, recovery was maintained (follow-up 18 months). By analogy to colorectal tumors, a new pathologic classification of these rare neoplasms may be proposed.