Pyrazolo[1,5-a]pyrimidin-7-yl phenyl amides as novel anti-proliferative agents: parallel synthesis for lead optimization of amide region
- 1 March 2005
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 15 (6) , 1591-1594
- https://doi.org/10.1016/j.bmcl.2005.01.066
Abstract
No abstract availableKeywords
This publication has 10 references indexed in Scilit:
- Knockout drug screensNature Biotechnology, 2001
- Use of isogenic human cancer cells for high-throughput screening and drug discoveryNature Biotechnology, 2001
- p53 Signaling and Cell Cycle CheckpointsChemical Research in Toxicology, 2001
- The Hallmarks of CancerCell, 2000
- CDK inhibitors: positive and negative regulators of G1-phase progressionGenes & Development, 1999
- Cell-cycle arrest versus cell death in cancer therapyNature Medicine, 1997
- p53, the Cellular Gatekeeper for Growth and DivisionCell, 1997
- When Checkpoints FailCell, 1997
- p21--Negative Regulator of the Cell CycleExperimental Biology and Medicine, 1996
- Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21Nature, 1996