Plasma Beta-2-Microglobulin and Fibronectin Levels in Beta-Thalassaemia

1 January 1984

journal article
research article
Published by S. Karger AG in Acta Haematologica

Vol. 71 (4) , 257-262
https://doi.org/10.1159/000206597

Abstract

The plasma .beta.2-microglobulin (.beta.2-MG) levels in 118 children with thalassemia were investigated. The mean level was higher than in healthy children. A significant increase of .beta.2-MG was associated with hypersplenism (3.14 .+-. 0.6 mg/l). The .beta.2-MG levels appeared to reflect RES activity but were not related to FE overload. Fibronectin levels were generally lower than in healthy adults; profound chronic fibronectin depletion was not accompanied by an increased liability to infection.

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