A Preliminary Study of Hypoglycemic Activity of Rubus fruticosus

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Abstract
A study of hypoglycemic activity of several extracts from R. fruticosus leaves was made in normoglycemic, hyperglycemic and alloxan-diabetic rabbits. Circulating insulin variations in normoglycemic rabbits were studied. The maximum decrease obtained in the blood glucose levels in normoglycemic rabbits was 20% after treatment with ethylic ether extracts. In glucose-induced hyperglycemia the maximum decrease was .apprx. 50%. In alloxan-diabetic rabbits the daily administration of 5 g/kg of the infusion caused a 15% decrease in the blood glucose levels. When this treatment was stopped, blood glucose levels began to rise reaching the initial values.

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