Biliary colic heralding systemic relapse in non-hodgkin lymphoma

Abstract
Though lymphocytic lymphoma often presents as a disseminated disease, involvement of the gallbladder or biliary tree in the absence of jaundice is very uncommon [1]. A patient with poorly differentiated lymphoma in complete clinical remission after combination chemotherapy experienced repeated episodes of biliary colic; at laparotomy her right‐upper‐quadrant pain was found to be due to lymphomatous involvement of the common bile duct. Recurrence in nodes surrounding the biliary tree heralded by several months the onset of a systemic relapse which did not respond to further cytotoxic therapy.