Preparation of human and murine monoclonal antibodies: antigens combined with or conjugated to lipopeptides constitute potent immunogens for in vitro and in vivo immunizations
- 1 December 1990
- journal article
- Published by SAGE Publications in Human Antibodies
- Vol. 1 (3) , 137-144
- https://doi.org/10.3233/hab-1990-1304
Abstract
Lipopeptide analogues of bacterial lipoprotein constitute polyclonal B lymphocyte activators. Combined with or covalently coupled to antigens, they act as potent adjuvants. We could show that antigens (BSA-DNP, TNP-SRBC, saxitoxin, HIV-1 gp160 (BH103Keywords
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