Chemotherapy of Neoplastic Disease

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Abstract
IN RECENT years there has been a remarkable increase in research directed toward the discovery of chemical substances of therapeutic value in neoplastic disease. This endeavor has been stimulated by many factors: the intensification of medical research in general and cancer research in particular; the notable examples set by the development of antibiotics for bacterial infections; public demand for effective methods of controlling the disease; and the ever-present, suffering, doomed, but often lingering, patient with cancer. Recent chemotherapeutic advances — estrogens in prostatic carcinoma, nitrogen mustards in the lymphomas and urethane in the leukemias — have provided some encouragement toward . . .