CARBAMAZEPINE AS ADJUNCTIVE TREATMENT IN NON-EPILEPTIC CHRONIC INPATIENTS WITH EEG TEMPORAL-LOBE ABNORMALITIES

  • 1 January 1983
    • journal article
    • research article
    • Vol. 44  (9) , 326-331
Abstract
A 15-wk double-blind, randomized, within-patient design was used to assess carbamazepine vs. placebo as adjunctive treatment in chronic hospitalized psychiatric inpatients (predominantly schizophrenic) with EEG temporal lobe abnormalities but no clinical evidence of epilepsy. A statistically significant improvement on carbamazepine was found on all clinical rating measures used (Overall Clinical Rating, Brief Psychiatric Rating Scale and Global Assessment). The results also appeared to be clinically significant.

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