Medical Therapy During the Menopause

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Abstract
The climacteric is a condition involving more than estrogen deficiency. Therefore the treatment of the climacteric is more complex than that of estrogen substitution. Furthermore the majority of menopause patients do not require estrogen substitution therapy. An appreciable minority of patients are benefited by neither sedation nor estrogen treatment. They are probably in need of psychiatric care and socio-economic readjustment. The Endocrine Clinic of Sloane Hospital for Women studied 91 consecutive patients. Eleven were referred to other clinics for treatment of disorders not related to the menopause. The 80 patients remaining were treated with phenobarbetal. Of these, 36 were relieved by phenobarbital alone. The 44 unrelieved patients were treated by estrogens, and relief was obtained in 20. There were 17 menopausal patients who were not relieved by phenobarbital or by estrogen or by both given concurrently.

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