CHARACTERIZATION OF ANTIGENS FROM ASPERGILLUS-FUMIGATUS .3. COMPARISON OF ANTIGENIC RELATIONSHIPS OF CLINICALLY IMPORTANT ASPERGILLI
- 1 January 1979
- journal article
- research article
- Published by Elsevier
- Vol. 120 (6) , 1297-1303
- https://doi.org/10.1164/arrd.1979.120.6.1297
Abstract
Antigenic relationships between strains of A. fumigatus, A. fumigatus var. ellipticus, A. phialiseptus, A. flavus and A. niger were analyzed by fused rocket immunoelectrophoresis and by skin tests. Of the antigens detected between strains and species of the A. fumigatus series, 73-89% were shared. Degree of sharing between antigens of A. flavus, A. fumigatus series and A. niger was much lower and ranged from 19-35%. In reciprocal skin tests in sensitized guinea pigs, similar relationships were shown. Three fractions of A. fumigatus extract were markedly specific for this species. Cross reactivity was associated primarily with carbohydrate and glycoprotein fractions.This publication has 2 references indexed in Scilit:
- Antigenic Relationships Among Species of Mycobacterium Studied by Fused Rocket ImmunoelectrophoresisInternational Journal of Systematic and Evolutionary Microbiology, 1978
- Pulmonary aspergillosis: Diagnostic and immunological significance of antigens and C‐substance in Aspergillus fumigatusThe Journal of Pathology and Bacteriology, 1964