Experimental Human Salmonellosis: I. Pathogenicity of Strains of Salmonella Meleagridis and Salmonella Anatum Obtained from Spray-Dried Whole Egg
- 1 May 1951
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 88 (3) , 278-289
- https://doi.org/10.1093/infdis/88.3.278
Abstract
Three strains each of S. meleagridis and S. anatum originally isolated from market samples of spray-dried whole egg powder were fed to human volunteers. Multiple dose levels were employed and the minimal infective dose for man was detd. for each strain. All 6 strains produced human illness. Clinical salmonellosis was produced in 32 men. The incubation period in 75% of the cases was from 20 to 48 hrs. and ranged from 8 to 72 hrs. The cases varied in severity from mild brief enteritis to serious prostrating illness. Wide variation in the infective dose occurred from strain to strain of the same species. The infective dose ranged from 0.58 million to 67.2 million. Many cases of asymptomatic carrier states were produced, some persisting for many weeks.Keywords
This publication has 2 references indexed in Scilit:
- SURVIVAL OF SALMONELLA IN RECONSTITUTED EGG POWDER SUBJECTED TO HOLDING AND SCRAMBLINGJournal of Food Science, 1948
- Some bacteriological aspects of dehydrated foodsEpidemiology and Infection, 1944