The N terminus of the murine p53 tumour suppressor is an independent regulatory domain affecting activation and thermostability

This publication has 29 references indexed in Scilit:

• Mdm2 promotes the rapid degradation of p53
  Nature, 1997
• Modification of Two Distinct COOH-terminal Domains Is Required for Murine p53 Activation by Bacterial Hsp70
  Journal of Biological Chemistry, 1996
• Allosteric Regulation of the Thermostability and DNA Binding Activity of Human p53 by Specific Interacting Proteins
  Published by Elsevier ,1996
• Temperature sensitivity for conformation is an intrinsic property of wild-type p53
  British Journal of Cancer, 1995
• Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations
  Science, 1994
• A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein.
  Genes & Development, 1993
• Wild-type p53 adopts a ‘mutant’-like conformation when bound to DNA.
  The EMBO Journal, 1993
• Definition of a consensus binding site for p53
  Nature Genetics, 1992
• Suppression of Human Colorectal Carcinoma Cell Growth by Wild-Type p53
  Science, 1990
• p53 transformation-related protein: Detection by monoclonal antibody in mouse and human cells
  Proceedings of the National Academy of Sciences, 1981