SOME OBSERVATIONS ON THE EFFECT OF HISTAMINE, 48/80 AND FIVE ANTIHISTAMINIC DRUGS OF THE SURVIVAL TIME OF ORTHOTOPIC SKIN HOMOGRAFTS IN THE MOUSE

1 April 1963

journal article
research article
Published by Wolters Kluwer Health in Transplantation

Vol. 1 (2) , 181-186
https://doi.org/10.1097/00007890-196301020-00005

Abstract

Fa a study of the effect of histamine, a histamine release agent (48/80) and five anti-histamines (triprolidine HCl, chlorcycEzine HCL mepyramine maleate, promethazine HCl and chlorpheniramine HCl) on the survival time of orthotopic first-set skin homografts in the mouse (A donor, CBA host) it has been shown that the increase observed was as great in the saline controls as in the drug treated animals.

Keywords

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Quantitative studies on tissue transplantation immunity IV. Induction of tolerance in newborn mice and studies on the phenomenon of runt disease
Philosophical Transactions Of The Royal Society B-Biological Sciences, 1959