The mechanism of alkylation of DNA by 5-(3-methyl-l-triazeno) imidazole-4-carboxamide (MIC), a metabolite of dic (NSC-45388) non-involvement of diazomethane
- 30 June 1974
- journal article
- research article
- Published by Elsevier in Chemico-Biological Interactions
- Vol. 8 (6) , 403-413
- https://doi.org/10.1016/0009-2797(74)90046-5
Abstract
No abstract availableKeywords
This publication has 20 references indexed in Scilit:
- Methylation of DNA by 3H-14C-methyl-labelled N-methyl-N-nitrosourea—Evidence for transfer of the intact methyl groupChemico-Biological Interactions, 1973
- Mechanism of action of 5-(3,3-dimethyl-1-triazeno)imidazole-4-caboxamide in mammalian cells in cultureBiochemical Pharmacology, 1972
- 5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamide (DTIC, DIC, NSC-45388)—A new antitumor agent with activity against malignant melanomaPublished by Elsevier ,1972
- Methylation of nucleic acids and urinary excretion of 14C-labeled 7-methylguanine by rats and man after administration of 4(5)-(3,3-Dimethyl-1-triazeno)-imidazole 5(4)-carboxomideToxicology and Applied Pharmacology, 1971
- Metabolism of 4(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide to 4(5)-aminoimidazole-5(4)-carboxamide in manBiochemical Pharmacology, 1970
- Mechanism of carcinogenesis with 1-Aryl-3,3-dialkyltriazenes. Enzymatic dealkylation by rat liver microsomal fraction in vitroBiochemical Pharmacology, 1969
- Imidazoles. II. 5(or 4)-(Monosubstituted Triazeno)imidazole-4(or 5)-carboxamides1Journal of Medicinal Chemistry, 1966
- Antitumor activity of triazenoimidazolesBiochemical Pharmacology, 1962
- Imidazoles. I. Coupling Reactions of 5-Diazoimidazole-4-carboxamide1,2The Journal of Organic Chemistry, 1962
- THE CONVERSION OF QUATERNARY PYRROLIDINIUM SALTS TO OPEN-CHAIN DIAMINESThe Journal of Organic Chemistry, 1944