Effect of mutations at Lys250, Arg251, and Lys253 of cytochrome P450 1A2 on the catalytic activities and the bindings of bifunctional axial ligands
- 1 October 1992
- journal article
- Published by Elsevier in Archives of Biochemistry and Biophysics
- Vol. 298 (1) , 198-203
- https://doi.org/10.1016/0003-9861(92)90113-b
Abstract
No abstract availableKeywords
Funding Information
- Ministry of Education, Culture, Sports, Science and Technology
- Asahi Glass Foundation
This publication has 15 references indexed in Scilit:
- High-resolution crystal structure of cytochrome P450camPublished by Elsevier ,2005
- Role of Glu318 at the putative distal site in the catalytic function of cytochrome P450dBiochemistry, 1992
- Crystal structure of the cytochrome P-450CAM active site mutant Thr252AlaBiochemistry, 1991
- Absorption spectral study of cytochrome P450d-phenyl isocyanide complexes: effects of mutations at the putative distal site on the conformational stabilityBiochemistry, 1991
- Ligand binding studies of engineered cytochrome P-450d wild type, proximal mutants, and distal mutantsBiochemistry, 1991
- Site-directed mutageneses of rat liver cytochrome P-450d: catalytic activities toward benzphetamine and 7-ethoxycoumarinBiochemistry, 1989
- Identification and location of .alpha.-helices in mammalian cytochromes P450Biochemistry, 1989
- Secondary structure prediction of 52 membrane-bound cytochromes P450 shows a strong structural similarity to P450camBiochemistry, 1989
- Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450Biochemical Pharmacology, 1985
- Studies on the microsomal mixed-function oxidase system: mechanism of action of hepatic NADPH-cytochrome P-450 reductaseBiochemistry, 1981