Aerogenic Immunization of the Monkey and Guinea Pig with Live Tularemia Vaccine

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Abstract
Studies were made on the clinical acceptability and immunogenicity of live tularemia vaccine administered by the dermal or respiratory route. Aerogenic as well as dermal vaccination proved inocuous. Animals vaccinated aerogenically showed higher levels of antibody and comparable if not greater protection against challenge with a highly virulent strain of Pasteurella tularensis than animals vaccinated dermally.

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