Shear Stress Increases ICAM-1 and Decreases VCAM-1 and E-selectin Expressions Induced by Tumor Necrosis Factor-α in Endothelial Cells

1 January 2004

journal article
research article
Published by Wolters Kluwer Health in Arteriosclerosis, Thrombosis, and Vascular Biology

Vol. 24 (1) , 73-79
https://doi.org/10.1161/01.atv.0000106321.63667.24

Abstract

Objective— Vascular endothelial cells (ECs) are subjected to shear stress and cytokine stimulation. We studied the interplay between shear stress and cytokine in modulating the expression of adhesion molecule genes in ECs.

Keywords

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