Studies on Short-lived Internal α-emitters in Mice and Rats

1 January 1971

journal article
research article
Published by Taylor & Francis in International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine

Vol. 20 (1) , 27-38
https://doi.org/10.1080/09553007114550841

Abstract

The distribution of intraperitonally-injected ²²⁴Ra was studied in NMRI mice and WISTAR rats. The highest activity concentrations were found in the skeleton. High radium concentrations were also obtained in the spleen (in mice higher than in rats, increasing with age). The calculated values were 12 rads/day for initial skeletal dose-rate and 30 rads for total averaged skeletal dose by supporting 1 μCi/kg ²²⁴Ra. The dose relationships of the short-lived ²²⁴Ra were contrasted to those of the long-lived ²²⁶Ra. Osteosarcoma-induction related to skeletal dose is discussed and compared with results of ²²⁶Ra known from the literature.

Keywords

This publication has 4 references indexed in Scilit:

Bone Cancers Induced by 224Ra (Th X) in Children and Adults
Health Physics, 1970
Malignancy from Radium
British Journal of Cancer, 1970
Radium and Radon Retention in Mice
Health Physics, 1963
Schwere Strahlenschäden nach der Peteosthorbehandlung von Kindern
Deutsche Medizinische Wochenschrift (1946), 1956