The formation of azoxymethane, a colon carcinogen, during the chemical oxidation of methylamine
- 1 January 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in Carcinogenesis: Integrative Cancer Research
- Vol. 1 (1) , 57-60
- https://doi.org/10.1093/carcin/1.1.57
Abstract
Simple chemical oxidation of methylamine in aqueous solution or in methanol leads to the formation of significant amounts of azoxymethane, a strong carcinogen in rodents. Methods, including high pressure liquid chromatography, differential pulse polarography and gas chromatography-mass spectrometry, used for the identification of the carcinogen, are described.Keywords
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