Discovery of New Therapeutic Targets by the Informational Spectrum Method
- 1 October 2008
- journal article
- review article
- Published by Bentham Science Publishers Ltd. in Current Protein & Peptide Science
- Vol. 9 (5) , 493-506
- https://doi.org/10.2174/138920308785915245
Abstract
The field of bioinformatics has become a major part of the drug discovery pipeline playing a key role in improvement and acceleration of this time and money consuming process. Here we review the application of the informational spectrum method (ISM), a virtual spectroscopy method for structure/function analysis of proteins, in identification of functional protein domains representing candidate therapeutic targets for drugs against human immunodeficiency virus (HIV)-1, anthrax, highly pathogenic influenza virus H5N1 and cardiovascular diseases.Keywords
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