Retinal Capillary Hemodynamics and VEP/Pressure Tolerance: Evidence of Retinal Microcirculatory Compromise in Treated Glaucomatous Eyes
- 1 January 1997
- journal article
- clinical trial
- Published by S. Karger AG in Ophthalmologica
- Vol. 211 (3) , 172-177
- https://doi.org/10.1159/000310785
Abstract
Measurements of retinal leukocyte velocity were made in single eyes of 6 glaucomatous adults and 9 normal subjects at each of 4 discrete levels of IOP elevation assigned according to the characteristics of prior pattern-evoked cortical potential pressure tolerance measurements. Glaucomatous eyes failed to demonstrate any stabilization in retinal leukocyte velocity at pressures above 45 mm Hg, with velocities 33% lower than normal for a comparable degree of IOP elevation (p < 0.012). Even at baseline IOP, leukocyte velocity was 27.2% slower in the treated glaucomatous eyes than in normal control eyes (p < or = 0.013), despite comparable baseline IOP levels in both groups.Keywords
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