Some Age-Related Structural Peculiarities of Fractionated Chromatin
- 1 January 1983
- journal article
- research article
- Published by S. Karger AG in Gerontology
- Vol. 29 (1) , 9-18
- https://doi.org/10.1159/000213089
Abstract
Thermal denaturation and electrophoretic mobility of liver and small intestinal mucosa fractionated chromatin and the DNA of chromatin fractions have been studied in young and old rats. During aging, the thermostability of chromatin increased, electrophoretic mobility of mono-, di-, and trinucleosomal fragments decreased at the expense of increased repeated length of nucleosomal DNA.Keywords
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