Plasmiogen-Plasmin System
- 1 December 1968
- journal article
- Published by Oxford University Press (OUP) in The Journal of Biochemistry
- Vol. 64 (6) , 743-750
- https://doi.org/10.1093/oxfordjournals.jbchem.a128957
Abstract
A simple method for preparation of human plasminogen of high purity from the euglobulin fraction of serum was reported. This method gave about 29-fold purification over euglobulin in about 70% yield. The preparation obtained Was homogeneous in ultracentrifugal analysis, Sephadex G-150 gel filtration and disc-electrophoresis (5hr run), but heterogenous in ion-exchange chromatography with DEAE-Sephadex A-50. The purified plasminogen was very soluble and stable in neutral salt solutions.Keywords
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