Asparagine Synthetase Chemotherapy
- 1 June 2006
- journal article
- review article
- Published by Annual Reviews in Annual Review of Biochemistry
- Vol. 75 (1) , 629-654
- https://doi.org/10.1146/annurev.biochem.75.103004.142520
Abstract
Modern clinical treatments of childhood acute lymphoblastic leukemia (ALL) employ enzyme-based methods for depletion of blood asparagine in combination with standard chemotherapeutic agents...Keywords
This publication has 197 references indexed in Scilit:
- How molecular profiling could revolutionize drug discoveryNature Reviews Drug Discovery, 2005
- Substrate-Induced Changes in the Ammonia Channel for Imidazole Glycerol Phosphate SynthaseBiochemistry, 2003
- Channeling of ammonia in glucosamine-6-phosphate synthaseJournal of Molecular Biology, 2001
- Dual Role for the Glutamine Phosphoribosylpyrophosphate Amidotransferase Ammonia ChannelPublished by Elsevier ,2000
- The Design of Leadlike Combinatorial LibrariesAngewandte Chemie International Edition in English, 1999
- Coupled Formation of an Amidotransferase Interdomain Ammonia Channel and a Phosphoribosyltransferase Active Site,Biochemistry, 1997
- Overproduction, preparation of monoclonal antibodies and purification of E.coli asparagine synthetase AProtein Engineering, Design and Selection, 1992
- TSH is able to induce cell cycle-related gene expression in rat thyroid cellBiochemical and Biophysical Research Communications, 1992
- L-Asparaginase and L-Asparagine MetabolismAnnual Review of Pharmacology, 1970
- Asparagine synthetase in asparaginase resistant and susceptible mouse lymphomasBiochemical and Biophysical Research Communications, 1968